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Nonanal-d<sub>18</sub>

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2607

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N8016S
    Nonanal-d18

    		Isotope-Labeled Compounds
    Nonanal-d18 is the deuterium labeled Nonanal[1]. Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity[2].
    <em>Nonanal-d</em><em>18</em>
  • HY-N8016S1
    Nonanal-d4

    		Isotope-Labeled Compounds
    Nonanal-d4 is deuterated labeled Methyl propyl disulfide (HY-N7436). Methyl propyl disulfide is an volatile sulfur-containing compound produced in garlic and onions with anticaner effect .
    <em>Nonanal-d</em>4
  • HY-N8016S2
    Nonanal-d2

    		Isotope-Labeled Compounds
    Nonanal-d2 is deuterated labeled Methyl cinnamate (HY-W017212). Methyl cinnamate (Methyl 3-phenylpropenoate), an active component of Zanthoxylum armatum, is a widely used natural flavor compound. Methyl cinnamate (Methyl 3-phenylpropenoate) possesses antimicrobial activity and is a tyrosinase inhibitor that can prevent food browning. Methyl cinnamate (Methyl 3-phenylpropenoate) has antiadipogenic activity through mechanisms mediated, in part, by the CaMKK2-AMPK signaling pathway .
    <em>Nonanal-d</em>2
  • HY-B0803S
    Lumefantrine-d18

    Benflumetol-d<sub>18sub>

    		 Isotope-Labeled Compounds Parasite Infection
    Lumefantrine-d18 is the deuterium labeled Lumefantrine, which is an antimalarial agent.
    Lumefantrine-d<em>18</em>
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-13017S2
    Ivacaftor-d18

    VX-770-d<sub>18sub>

    		 Autophagy CFTR Endocrinology
    Ivacaftor-d18 is the deuterium labeled Ivacaftor[1]. Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively[2].
    Ivacaftor-d<em>18</em>
  • HY-17367S1
    Atazanavir-d18

    BMS-232632-d<sub>18sub>

    		 Isotope-Labeled Compounds HIV Infection
    Atazanavir-d18 is the d18 labled Atazanavir (HY-17367). Atazanavir is a selective HIV-1 protease inhibitor .
    Atazanavir-d<em>18</em>
  • HY-W013812S
    Ethyl linoleate-13C18

    Linoleic Acid-13C<sub>18sub> ethyl ester; Mandenol-13C<sub>18sub>

    		 Isotope-Labeled Compounds Cardiovascular Disease
    Ethyl linoleate- 13C18 is the 13C labeled Ethyl linoleate. Ethyl linoleate inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators[1].
    Ethyl linoleate-13C<em>18</em>
  • HY-103447S1
    Zearalenone-13C18

    Mycotoxin F2-13C<sub>18sub>; Toxin F2-13C<sub>18sub>

    		 Isotope-Labeled Compounds Others
    Zearalenone- 13C18 (Mycotoxin F2- 13C18; Toxin F2- 13C18) is the 13C labeled Zearalenone (HY-103447) . Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts .
    Zearalenone-13C<em>18</em>
  • HY-D0875S
    PIPES-d18

    1,4-Piperazinediethanesulfonic acid-d<sub>18sub>

    		 Isotope-Labeled Compounds
    PIPES-d18 is the deuterium labeled PIPES[1]. PIPES (1,4-Piperazinediethanesulfonic acid) is an important component of PIPES buffer agent used in biochemistry[2].
    PIPES-d<em>18</em>
  • HY-W101642S
    1,3-Diisopropylbenzene-d18

    m-Diisopropylbenzol-d<sub>18sub>

    		 Isotope-Labeled Compounds Others
    1,3-Diisopropylbenzene-d18 is the deuterium labeled 1,3-Diisopropylbenzene[1].
    1,3-Diisopropylbenzene-d<em>18</em>
  • HY-N1446S2
    Oleic acid-13C18

    9-cis-Octadecenoic acid-13C<sub>18sub>; 9Z-Octadecenoic acid-13C<sub>18sub>

    		 Na+/K+ ATPase Endogenous Metabolite Apoptosis Metabolic Disease Cancer
    Oleic acid- 13C18 is the 13C labeled Oleic acid. Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid[1]. Oleic acid is a Na+/K+ ATPase activator[2].
    Oleic acid-13C<em>18</em>
  • HY-131113S
    N-Nitrosodibutylamine-d18

    N-Nitroso-di-n-butylamine-d<sub>18sub>

    		 Isotope-Labeled Compounds Others
    N-Nitrosodibutylamine-d18 is the deuterium labeled N-Nitrosodibutylamine[1]. N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water[2].
    N-Nitrosodibutylamine-d<em>18</em>
  • HY-W288788S
    5-Methylheptan-3-ol-d18

    5-Methyl-3-heptanol-d<sub>18sub>

    		 Isotope-Labeled Compounds Others
    5-Methylheptan-3-ol-d18 is the deuterium labeled 5-Methylheptan-3-ol[1].
    5-Methylheptan-3-ol-d<em>18</em>
  • HY-10844S1
    Pretomanid-d5

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    		 Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-148682S1
    18β-Glycyrrhetyl-3-O-sulfate-d2

    Glycyrrhetic acid 3-O-hydrogen sulfate-d<sub>2sub>

    		 Isotope-Labeled Compounds Others
    18β-Glycyrrhetyl-3-O-sulfate-d2 is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682)[1].
    <em>18</em>β-Glycyrrhetyl-3-O-sulfate-d2
  • HY-148682S2
    18β-Glycyrrhetyl-3-O-sulfate-d3

    Glycyrrhetic acid 3-O-hydrogen sulfate-d<sub>3sub>

    		 Isotope-Labeled Compounds Others
    18β-Glycyrrhetyl-3-O-sulfate-d3 is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682)[1].
    <em>18</em>β-Glycyrrhetyl-3-O-sulfate-d3
  • HY-W023144S
    tris(1-Chloropropan-2-yl) phosphate-d18

    Tris(1-chloro-2-propyl) phosphate-d<sub>18sub>

    		 Isotope-Labeled Compounds Others
    tris(1-Chloropropan-2-yl) phosphate-d18 (Tris(1-chloro-2-propyl) phosphate-d18) is a deuterium labeled compound.
    tris(1-Chloropropan-2-yl) phosphate-d<em>18</em>
  • HY-W015829S
    N1,N1,N3,N3-Tetramethylpropane-1,3-diamine-d18

    Tetramethylpropylenediamine-d<sub>18sub>

    		 Isotope-Labeled Compounds Others
    N1,N1,N3,N3-Tetramethylpropane-1,3-diamine-d18 is the deuterium labeled N1,N1,N3,N3-Tetramethylpropane-1,3-diamine[1].
    N1,N1,N3,N3-Tetramethylpropane-1,3-diamine-d<em>18</em>
  • HY-125833
    Alpha-Naphthoflavone
    5 Publications Verification

    		 Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis Cancer
    Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .
    Alpha-Naphthoflavone
  • HY-157440
    AChE/Aβ-IN-3

    		Amyloid-β Reactive Oxygen Species Cholinesterase (ChE) Neurological Disease
    AChE/Aβ-IN-3 (compound AM5) is a dual inhibitor of AChE and Amyloid-β aggregation with IC50<.sub> values of 1.29 and 4.93 μM, respectively. AChE/Aβ-IN-3 has antioxidant properties that scavenge ROS and restore their normal levels. AChE/Aβ-IN-3 can be used in the study of neurological diseases, such as Alzheimer's disease .
    AChE/Aβ-IN-3
  • HY-144290
    ARN25068

    		GSK-3 DYRK Neurological Disease
    ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation .
    ARN25068
  • HY-N7118
    Clindamycin hydrochloride monohydrate

    		Bacterial Antibiotic Infection Cancer
    Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla) .
    Clindamycin hydrochloride monohydrate
  • HY-129946
    Dopamine D2 receptor antagonist-1

    		Dopamine Receptor Neurological Disease
    Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity .
    Dopamine D2 receptor antagonist-1
  • HY-163129
    BPU

    		Apoptosis MMP Cancer
    BPU arrests cell cycle progression in the sub-G1 phase. BPU is an anticancer agent through inhibiting blood vessel formation in tumor tissues .
    BPU
  • HY-139823A
    PRMT5-IN-11

    		Histone Methyltransferase Others
    PRMT5-IN-11 is a promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex in the (sub)micromolar range.
    PRMT5-IN-11
  • HY-144220
    NLRP3/AIM2-IN-1

    		NOD-like Receptor (NLR) Inflammation/Immunology
    NLRP3/AIM2-IN-1 is a thermal sepsis inhibitor with an < b > IC < sub > 50 < / sub > < / b > value of 3.136 ± 0.7667 μ M.
    NLRP3/AIM2-IN-1
  • HY-N11799
    Neochilenin

    3-O-Methylquercetin 4′-O-glucoside

    		 Others Others
    Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .
    Neochilenin
  • HY-157728
    ML307

    		E1/E2/E3 Enzyme Inflammation/Immunology
    ML307 is a potent, sub-micromolar, first-in-class Ubc13 enzyme activity inhibitor with an IC50 of 781 nM. ML307 has the potential for immunomodulation and inflammation research .
    ML307
  • HY-111258
    GSK345931A

    		Prostaglandin Receptor Neurological Disease Inflammation/Immunology
    GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain .
    GSK345931A
  • HY-P3426
    BACE1-IN-10

    		Beta-secretase Cancer
    BACE1-IN-10 is a potent BACE1 Inhibitor. BACE1-IN-10 shows sub-micromolar activity against recombinant BACE1 (rBACE1) .
    BACE1-IN-10
  • HY-P5856
    αA-Conotoxin PIVA

    		nAChR Neurological Disease
    αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC50 for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively. αA-Conotoxin PIVA can be used in the study of neurological diseases.
    αA-Conotoxin PIVA
  • HY-B1455
    Clindamycin
    5 Publications Verification
    Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria .
    Clindamycin
  • HY-111673
    8-CPT-Cyclic AMP sodium

    8-CPT-cAMP sodium; 8-(p-Chlorophenylthio)-cAMP sodium

    		 PKA Phosphodiesterase (PDE) Inflammation/Immunology
    8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). 8-CPT-Cyclic AMP sodium is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM. 8-CPT-Cyclic AMP sodium also inhibits PDE III and PDE IV with IC50 s of 24 and 25 μM, respectively. 8-CPT-Cyclic AMP sodium is a very high affinity for Epac and is a potent Epac activator .
    8-CPT-Cyclic AMP sodium
  • HY-U00037
    Ecopladib

    PLA 725

    		 Phospholipase Inflammation/Immunology
    Ecopladib is a sub-micromolar inhibitor of cytosolic phospholipase A2α (cPLA2α), with IC50s of 0.15 μM and 0.11 μM in the GLU micelle and rat whole blood assays, respectively.
    Ecopladib
  • HY-111192
    IPR-803
    1 Publications Verification

    		 Ser/Thr Protease Cancer
    IPR-803 is a potent inhibitor of the uPAR•uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity .
    IPR-803
  • HY-144238
    mPGES1-IN-6

    		PGE synthase Inflammation/Immunology
    MPGES-1 is considered as a promising therapeutic target of the next generation anti-inflammatory drugs in the research of inflammatory diseases. The < b > IC < sub > 50 < / sub > < / b > value of mPGES1-IN-6 is 0.03 μ M。
    mPGES1-IN-6
  • HY-W102714
    1,2-Cyclohexylenedinitrilotetraacetic acid

    CDTA

    		 Others Metabolic Disease
    1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .
    1,2-Cyclohexylenedinitrilotetraacetic acid
  • HY-144232
    Anticancer agent 28

    		Others Cancer
    Anticancer agent 28 showed good antitumor activity in H22 allogeneic mice in vivo. Its potency in K562 cells was 50 times that of oridonin, and its < b > IC < sub > 50 < / sub > < / b > value was 0.09 μ M。
    Anticancer agent 28
  • HY-W011474
    Geranylgeraniol

    		NF-κB Inflammation/Immunology
    Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .
    Geranylgeraniol
  • HY-18961
    PD 407824

    PD 407824 is a checkpoint kinase Chk1 and WEE1 inhibitor with IC50s of 47 and 97 nM, respectively. PD 407824 is a chemical BMP sensitizer and increases the sensitivity of cells to sub-threshold amounts of BMP4 .
    PD 407824
  • HY-118423
    SJ-3366

    IQP-0410

    		 HIV Inflammation/Immunology
    SJ-3366 (IQP-0410) is a potent inhibitor of HIV nonnucleoside reverse transcriptase . SJ-3366 (IQP-0410) inhibits HIV at sub-nanomolar concentrations primarily through a typical non-nucleoside mechanism .
    SJ-3366
  • HY-147781
    Anticancer agent 66

    		Apoptosis Cancer
    Anticancer agent 66 (Compound 13e) is an anti-cancer agent. Anticancer agent 66 induces apoptosis and increases sub-G1 cell population in MCF-7 cells. Anticancer agent 66 is a ciprofloxacin analog .
    Anticancer agent 66
  • HY-147782
    Anticancer agent 67

    		Apoptosis Cancer
    Anticancer agent 67 (Compound 13g) is an anti-cancer agent. Anticancer agent 67 induces apoptosis and increases sub-G1 cell population in MCF-7 cells. Anticancer agent 67 is a ciprofloxacin analog .
    Anticancer agent 67
  • HY-B1455S
    Clindamycin-d3 hydrochloride

    		Bacterial Antibiotic Parasite Infection
    Clindamycin-d3 (hydrochloride) is the deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria[1][2].
    Clindamycin-d3 hydrochloride
  • HY-135845
    TP3011

    CH0793011

    		 Topoisomerase Cancer
    TP3011 (CH0793011) is an active metabolite of CH-0793076 and is a potent topoisomerase I inhibitor equipotent as SN38 . TP3011 is against cancer cell lines growth with IC50s at the range sub-nanomolar in vitro .
    TP3011
  • HY-149033
    Kobusine derivative-2

    		Others Cancer
    Kobusine derivative-2, a kobusine derivative, has antiproliferative activity against cancer cells. Kobusine derivative-2 can induce the arrest of MDA-MB-231 cells in the sub-G1 phase. Anticancer activity .
    Kobusine derivative-2
  • HY-103235
    NPEC-caged-(S)-AMPA

    		iGluR Neurological Disease
    NPEC- caged-(S)-AMPA, a caged neurotransmitter analog, is a NPEC photoprotecting group caged the (S)-AMPA (HY-100815A) to make caged ligands specific for glutamate receptor sub-types. NPEC- caged-(S)-AMPA selectively activates AMPA receptor .
    NPEC-caged-(S)-AMPA
  • HY-B1455S1
    Clindamycin-13C,d3

    		Isotope-Labeled Compounds Bacterial Antibiotic Parasite Infection
    Clindamycin- 13C,d3 is the 13C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria[1][2][3].
    Clindamycin-13C,d3

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